Black Death in the rural cemetery of Saint-Laurent-de-la-Cabrerisse Aude-Languedoc, southern France, 14th century: immunological evidence

Abstract

An excavation carried out in 2007 in Saint-Laurent-de-la-Cabrerisse (Aude-Languedoc, southern France), revealed a medieval rural cemetery used during the 8th–14th centuries. One hundred and forty nine graves were identified. Amongst those, three burials radiocarbon dated to the 14th century contained the remains of several individuals. No paleotraumatological evidences of violence due to warfare or to a civil massacre were identified in the exhumed skeletons. Therefore, we hypothesized that the simultaneous inhumations could have occurred during the “Black Death” outbreak or during one of its resurgences. A rapid diagnostic test for the detection of Yersinia pestis F1 antigen was applied to the nine putative plague victims to authenticate the cause of their death. Seven of the nine individuals tested from the three graves were positive to Y. pestis F1 antigen. We additionally tested fourteen skeletons from single graves archaeologically dated to the 13th–14th centuries. Four of them were positive to Y. pestis F1 antigen, thus showing a higher mortality rate due to plague than originally expected. The Saint-Laurent-de-la-Cabrerisse plague victims are the oldest samples from which Y. pestis F1 antigen has been, hitherto, identified. Few rural French cemetery containing plague victims have previously been identified and amongst them, only one dates to the 14th century. In the present report, we provide suggestive evidence of a second rural cemetery from southern France where victims of Y. pestis infection were buried. Our findings provide new information about the management of the plagued corpses during the “Black Death” in small rural communities.