Abstract

Bisphenol-A (BPA) has been shown to be an endocrine disruptor in animals. We have previously demonstrated selective extraction of BPA from dental materials and its detection by gas chromatography-mass spectrometry. In the present study, this same procedure was employed for the detection of BPA in materials routinely used in pediatric dentistry—commercial resin composites, fissure sealants, compomers, and dentin bonding agents. In unpolymerized materials, significant BPA contamination was detected in 2 of 3 resin composites, 2 of 5 fissure sealants, and all bonding agents and intermediate resins tested. Moreover, in most cases, incubation of polymerized materials for 24 h resulted in release of BPA into phosphate-buffered saline. However, the highest level of BPA released (89.5 ng/g polymerized material) was still far less than the reported lowest dose that produces endocrine disruption in experimental animals (2 μg/kg/d).

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.