Bispectral Monitoring As An Adjunct To Nurse Administered Propofol Sedation

Abstract

Background: Bispectral monitoring (BIS) provides a non-invasive measure of the level of sedation. BIS has been shown to lag behind the level of sedation during induction and emergence of sedation with propofol. We sought to determine whether BIS is a useful adjunctive maneuver to registered nurse administered propofol (NAPS). Methods: A randomized controlled trial was performed. BIS was recorded continuously in all subjects. In the first phase of the study, 47 patients were randomized to have BIS visible to the nurse and endoscopist versus BIS invisible to nurse and endoscopist.