Bis(N,N‐diisopropylamino)trimethylsiloxy‐phosphane: A Novel Flexible Phosphitylating Reagent in Nucleoside Chemistry and Its Application in the Synthesis of P‐Modified Nucleotides

Abstract

Dinucleotides such as 3, with reactive groups on phosphorus, can be readily prepared starting with the title compound 1. The first step is.conversion of 1 into the silylphosphites 2, compounds whose synthetic potential has certainly not yet been exhausted.