BISAP plus serum lactate dehydrogenase: a new scoring system for assessment of severity of acute pancreatitis

Abstract

Background: Acute Pancreatitis is a process of acute inflammation of pancreas along with peripancreatic tissue and multi organ involvement. To reduce morbidity and mortality by predicting the course of the disease and do an early intervention several scoring systems have been proposed such as RANSON’S score, BISAP score, APACHE II etc. Methods: Patients are chosen with clinical diagnosis of acute pancreatitis over a period of 6 months, based on inclusion criteria, with consent. They underwent investigations base d on the scoring systems and institutional protocol. The different scoring systems were used and calculated. The effectiveness of all the scoring systems were calculated using Microsoft Excel indicating its sensitivity, specificity, accuracy, positive and negative predictive value. Results: BISAP with LDH (BISAP PLUS) shows the highest sensitivity (85.71%), Positive predictive value (70.59%), Negative predictive value (84.62%) and Accuracy (76.67%) among different scoring systems. The highest specificity was seen in APACHE II (75%) Conclusions: Use of BISAP plus serum LDH (BISAP plus) can help in daily assessment and quicker management of acute pancreatitis and should be studied further, as it is showing promise in helping in management of acute pancreatitis.