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Abstract
Methylated 6A,6D-diamino 6A,6D-dideoxy β-cyclodextrin 4 was coupled with three cholesterol substituted glutaric or succinic acids 5– 7 to give amphiphilic cyclodextrins 1– 3 with good yields. The succinic acid derivative 1, a typical member of this new family, has shown good compatibility with phosphatidyl choline monolayer and bilayer as confirmed by deuterium magnetic nuclear resonance ( 2H NMR).
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