Abstract
Objective: To describe two cases of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) with testicular sperm in men with immotile cilia syndromes. Design: Case report. Setting: A university-based male infertility clinic and assisted reproduction unit. Patient(s): Two couples with male factor infertility due to Kartagener/immotile cilia syndrome. Intervention(s): IVF/ICSI with testicular sperm. Main outcome measure(s): Semen characteristics, sperm viability, fertilization rate, and pregnancy. Result(s): With testicular sperm, the two pronuclear fertilization rates were 63% and 60% in two cases. One case resulted in the birth of normal healthy girl. Conclusion(s): With testicular sperm, successful oocyte fertilization after ICSI in couples with male Kartagener/immotile cilia syndrome is possible despite the lack of sperm motility.
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