Abstract

URSM (Urorectal Septum Malformation Sequence) in humans is a well-known specific developmental abnormalities originally described in about 25 years ago including the absence of anal, urethral and vaginal openings, ambiguous genitalia and genito-urinary anomalies 1. Before the introduced the term in human medicine, authors used the terms including ‘female pseudohermaphroditism with anorectal malformation, hypoplastic pelvic outlet and persistent cloaca’ 2. The extent of variation in human URSM cases is from complete to partial or milder variant forms characterized by a single openining draining the cloaca might be compatible with life 3.

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