Abstract
Three cases are presented in which the patient has the primary diagnosis of post-traumatic stress disorder (PTSD) and an unrecognized coexisting diagnosis of bipolar disorder. Treatment with lithium carbonate substantially decreased the intensity of their symptoms and improved their functioning in daily life events. There is little in the literature regarding the coexistence of PTSD and other psychiatric diagnoses, which may indicate an underdiagnosis and undertreatment of the coexisting diagnosis. The similarity between the symptoms and course of PTSD and bipolar disorder makes distinguishing these disorders in a single patient difficult. It appears that bipolar disorder may exist in a significant number of patients with PTSD who show little improvement over time and have a significant impairment in daily life activities.
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