Abstract
Abstract The fungus Rhizopus arrhizus has been used for the reduction of acetophenone and its o -, m - and p -methoxy derivatives 1a–d to the corresponding ( S )-(−)-alcohols. Their racemic acetates were also hydrolyzed to ( R )-(+)-alcohols. The analysis of products revealed that maximum enantioselectivity (78–88 %ee) could be obtained using m -methoxy acetophenone as substrate.
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