Abstract
Natural products are chemicals used in many industrial processes due to their various pharmacological or biological actions. Microorganisms can catalyze reactions that allow modification of structures of phytochemicals and organic compounds. Hereby, it is possible to obtain valuable products with regio- and stereo-selective reactions. The aim of the paper was to biotransform several terpenes and terpenoids including (−)-α-pinene, β-ionone and isophorone by using A. niger NRRL 326 and to determine their biotransformation products and biological activities. According to the GC-MS analysis, the following compounds were obtained: (S)-(+)-carvone hydrate (4.28%) from (−)-α-pinene; 4-hydroxybetaionone (48.33%), 2-hydroxybetaionone (22.40%), α-ionone (1.29%) and dihydro-3-oxo-beta-ionol (1.11%) from β-ionone; 4-hydroxyisophorone (55.54%), 3,3-dimethyl-5-oxo-cyclohexanecarboxaldehyde (1.87%), 4-ketoisophorone (1.22%) and dihydrooxoisophorone (0.59%) from isophorone. The biological activities of the extracts were found to be slightly higher than the control experiments. The findings obtained will contribute to the literature and A. niger NRRL 326 have the potential to become an important biotransformation agent.
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