Abstract
AbstractBiotransformation of oleaside A (1) by Cunninghamella echinulata (ACCC 30369) was carried out to afford two products, (6R)‐6‐hydroxyoleaside A (2) and (7S)‐7‐hydroxyoleaside A (3). The structures of 2 and 3 were elucidated by extensive NMR analyses and further confirmed by single‐crystal X‐ray diffraction analysis. We also report herein the X‐ray diffraction structure of oleaside A (1) for the first time. Compounds 1–3 were evaluated for their cytotoxic activities against the A549, HCT116, HepG2, and HL‐60 human cancer cell lines.
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