Abstract
Thanks to a better understanding of the role of type 2 inflammation in allergic asthma, progress has been made in the development of new biologic therapies targeting these specific pathways. After adults, these treatments are now available for children. However, with the exception of Omalizumab, an anti-IgE immunoglobulin, very few studies have been published on the efficacy and safety of biologic therapies in children, in particular anti-interleukin-5 (IL5) and anti-IL4/IL13 therapies. After exclusion of differential diagnoses, exclusion if difficult to treat asthma and phenotyping, a personalized biologic therapy could be proposed with specificities in children regarding the initiation, follow-up and duration of treatment.© 2020 SPLF. Published by Elsevier Masson SAS. All rights reserved.
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