Abstract
The use of a pleated, tangential flow microfiltration module has been investigated in the context of three areas of biotechnology: (a) industrial scale harvesting of microorganisms, (b) diafiltrative separation of a low molecular weight protein, from a homogenate of soft animal tissue, and (c) the removal of fat and casein particulates from cheese whey prior to concentration of the whey by ultrafiltration. In all three applications, low pressure membrane microfiltration technology can be used to either improve the overall efficiency and performance of centrifugal separations or to replace them entirely. In the case of prefiltration of cheese whey, significant improvement was achieved both for the recovery of butter fat as well as increased UF membrane flow rates in the concentration step.
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