Abstract
In the biosynthesis of (25S)-steroidal sapogenins in tissue cultures of Dioscorea tokoro Makino fed with sodium [1, 2-13C2] acetate, the 13C n.m.r. spectra of the 13C-labelled (25 S)-sapogenins (3) and (4) indicated (i) that a hydrogen atom at C-25 was introduced from the 25-si face of the Δ24 double bond of Δ24-biosynthetic intermediates as in the case of the (25R)-sapogenins (1) and (2), and (ii) that oxidation of the pro-R methyl group (C-26) of cholesterol was accelerated by a higher concentration of sodium acetate giving (25S)-steroidal sapogenins.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Chemical Communications
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
