Abstract

DL-{4,5- 13 C 2 , 6- 14 C]Lysine is incorporated specifically, and via a symmetrical intermediate, into ring A of vertine {11} and lythrine {10}; the cis- and traans-quinolizidinones, 25 and 19, are, respectively and specifically, effective precursors for 11 and 10, and the corresponding mono-O-methyl ethers 15, 17, 21, and 23 are nor effectively utilized foralkaloid biosynthesis

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