Abstract
ABSTRACTSageretia thea (Osbeck.) was used as an effective chelating agent for the biosynthesis of iron oxide nanoparticles (IONP's) and extensively characterized through XRD, FTIR, Raman spectroscopy, Energy Dispersive Spectroscopy, HR-SEM/TEM and SAED. Antibacterial assays against five human pathogenic bacterial strains were carried out and minimum inhibitory concentrations were calculated. Pseudomonas aeruginosa (MIC: 7.4 µg/mL) was the most susceptible strain to biosynthesized IONPs. All of the fungal strains showed susceptibility to the IONPs. MTT cytotoxic assay was carried out against the promastigote and amastigote cultures of Leishmania tropica and their IC50 values were calculated as 17.2 and 16.75 µg/mL. The cytotoxic potential was further assessed using brine shrimps, and the IC50 was calculated as 16.46 µg/mL. Moderate antioxidant activities were reported. Human RBCs and macrophages were found to be biocompatible with biogenic IONPs (IC50 > 200 µg/mL).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
