Abstract
The source of oxaloacetic acid, required for the synthesis of porphyrins in Arthrobacter hyalinus, was examined by means of a feeding experiment with [1, 3-13C2]glycerol, which is transformed to pyruvic acid. A half of the carbon dioxide liberated from pyruvic acid in the formation of acetyl CoA was utilized for carboxylation of pyruvic acid to generate oxaloacetic acid.
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