Biosynthesis and Antimicrobial Activity of Semiconductor Nanoparticles against Oral Pathogens.

C. Malarkodi,G. Gnanajobitha,G. Annadurai,K. Paulkumar,S. Rajeshkumar,M. Vanaja

doi:10.1155/2014/347167

C. Malarkodi, G. Gnanajobitha + Show 4 more

Open Access

https://doi.org/10.1155/2014/347167

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Abstract

Dental care is an essential phenomenon in human health. Oral pathogens can cause severe break which may show the way to serious issues in human disease like blood circulation and coronary disease. In the current study, we demonstrated the synthesis and antimicrobial activity of cadmium sulphide and zinc sulphide nanoparticles against oral pathogens. The process for the synthesis of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles is fast, novel, and ecofriendly. Formation of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles was confirmed by surface plasmon spectra using UV-Vis spectrophotometer. The morphology of crystalline phase of nanoparticles was determined from transmission electron microscopy (TEM) and X-ray diffraction (XRD) spectra. The average size of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles was in the range of 10 nm to 25 nm and 65 nm, respectively, and the observed morphology was spherical. The results indicated that the proteins, which contain amine groups, played a reducing and controlling responsibility during the formation of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles in the colloidal solution. The antimicrobial activity was assessed against oral pathogens such as Streptococcus sp. Staphylococcus sp. Lactobacillus sp., and Candida albicans and these results confirmed that the sulphide nanoparticles are exhibiting good bactericidal activity.

Highlights

Dental caries and periodontal disease, the majority widely increased disease affecting mankind, occupy the devotion of microbes and expansion of biofilm on the natural and restored tooth surface
The present study shows the synthesis of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles by using the bacteria, K. pneumoniae
The present study reports the biological synthesis of sulphide nanoparticles like CdS and ZnS using the bacteria K. pneumoniae

Summary

Introduction

Dental caries and periodontal disease, the majority widely increased disease affecting mankind, occupy the devotion of microbes and expansion of biofilm on the natural and restored tooth surface . In this framework, a biofilm can be classed as an aggregate of bacteria in which cells stay to each other and to an outside [1]. Nanostructured materials are a technically significant object that possesses optical and electrical properties that depend powerfully on the size and shape of the nanoparticles. UV-Vis spectrophotometer was used to characterize the synthesized sulphide nanoparticles

Materials and Methods

Result and Discussion

Synthesis of Sulphide Nanoparticles

Conclusion