Abstract
Fluorescent lanthanide chelates and their detection using time-resolved fluorimetry for in vitro studies are discussed. Time-resolved fluoroimmunoassays with dissociation of the lanthanide ion to the solution are very sensitive and are today widely employed in clinical laboratories. In many applications directly fluorescent chelates are needed, but they do not yet offer a comparable sensitivity. It is concluded that dissociation enhanced time-resolved fluorimetry provides a sensitivity comparable to that of phosphorus-32 in DNA hybridization assays. Fluorescent lanthanide chelates are a promising new group of labels for in vitro biospecific assays.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
