Biosensors Based on Plasmonics

Abstract

Because of the sensitivity to refractive index changes, plasmonics nanostructures have been investigated broadly for the bio-molecules detection through the excitations of the propagating surface plasmon resonance (PSPR) or localized surface plasmon resonance (LSPR). PSPR sensors can detect sub-monolayer quantities of bio-molecules at the gold film surface and provide real-time data through continuous optical measurements. LSPR sensors could be more sensitive to local refractive index changes and the factors of nanoparticle material, shape and size are all interrelated and contribute to the refractive index sensitivities.