Biosensors And Their Applications in The Detection of Cancer Biomarkers

Abstract

Cancer is a critical disease that seriously affects human health and has a high mortality rate. Therefore, it is very important to effectively improve the survival rate of patients. The low survival rate of cancer is because it can’t be effectively diagnosed in the early stage. When most cancers are in the advanced stage after imaging examination, cancer cells have spread in the body or even metastasized, and the difficulty of treatment will be greatly increased after the metastasis occurs. Therefore, early detection of cancer is one of the key factors to improve the survival rate. However, imaging tests such as computer tomography and nuclear magnetic resonance imagining cannot accurately detect small lesions in the early stage of cancer, which also leads to low detection accuracy. In recent years, the interest in the development of biosensors has become more and more intense. Biosensors have shown excellent detection performance and real-time detection capability. Besides, biosensors can also detect biomarkers with extremely low content in detection samples, which is helpful for early cancer diagnosis. In addition, biosensors have also shown the potential to simultaneously detect multiple biomarkers.