Bioreactor operation for the production of exotoxin A by Pseudomonas aeruginosa

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Biotechnology and BioengineeringVolume 34, Issue 9 p. 1214-1220 Communications to the EditorFree Access Bioreactor operation for the production of exotoxin A by Pseudomonas aeruginosa Ilse I. Blumentals, Ilse I. Blumentals Department of Chemical Engineering, The Johns Hopkins University, Baltimore, Maryland 21218Search for more papers by this authorRobert M. Kelly, Robert M. Kelly Department of Chemical Engineering, The Johns Hopkins University, Baltimore, Maryland 21218Search for more papers by this authorJoseph Shiloach, Corresponding Author Joseph Shiloach Biotechnology Unit, Bldg 6, B1-33, NIDDK The National Institutes of Health Bethesda, Maryland 20892Biotechnology Unit, Bldg 6, B1-33, NIDDK The National Institutes of Health Bethesda, Maryland 20892Search for more papers by this author Ilse I. Blumentals, Ilse I. Blumentals Department of Chemical Engineering, The Johns Hopkins University, Baltimore, Maryland 21218Search for more papers by this authorRobert M. Kelly, Robert M. Kelly Department of Chemical Engineering, The Johns Hopkins University, Baltimore, Maryland 21218Search for more papers by this authorJoseph Shiloach, Corresponding Author Joseph Shiloach Biotechnology Unit, Bldg 6, B1-33, NIDDK The National Institutes of Health Bethesda, Maryland 20892Biotechnology Unit, Bldg 6, B1-33, NIDDK The National Institutes of Health Bethesda, Maryland 20892Search for more papers by this author First published: November 1989 https://doi.org/10.1002/bit.260340913AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 B. H. Iglewski and D. Kabat, Proc. Natl. Acad. Sci. USA., 72, 2284 (1975). 2 L. F. Hanne, T. R. Howe, and B. H. Iglewski, J. Bacteriol., 154, 383 (1983). 3 S. H. Leppla, O. C. Martin, and L. A. Muehl, Biochem. Biophys. Res. Commun., 40, 1437 (1978). 4 S. Lory and R. J. Collier, Infect. Immun., 28, 494 (1980). 5 M. L. Vasil, C. Chamberlain, and C. C. R. Grant, Infect. Immun., 52, 538 (1986). 6 M. J. Bjorn, B. H. Iglewski, S. K. Ives, J. C. Sadoff, and M. L. Vasil, Infect. Immun., 19, 789 (1978). 7 R. M. DeBell, Infect. Immun., 24, 132 (1979). 8 P. V. Liu, J. Infect. Dis., 128, 506 (1973). 9 I. I. Blumentals, R. M. Kelly, M. Gorziglia, J. B. Kaufman, and J. Shiloach, Appl. Environ. Microbiol., 53, 2013 (1987). 10 C. C. R. Grant and M. L. Vasil, J. Bacteriol., 168, 1112 (1986). 11 S. Lory, J. Bacteriol., 168, 1451 (1986). 12 G. L. Gray and M. L. Vasil, J. Bacteriol, 147, 275 (1981). 13 R. C. Hedstrom, C. R. Funk, J. B. Kaper, O. R. Pavlovskis, and D. R. Galloway, Infect. Immun., 51, 37 (1986). 14 V. L. Miller and J. J. Mekalanos, Proc. Natl. Acad. Sci. USA. 81, 3471 (1984). 15 V. L. Miller and J. J. Mekalanos, J. Bacteriol., 163, 580 (1985). 16 M. L. Vasil, D. Kabat, and B. H. Iglewski, Infect. Immun., 16, 353 (1977). 17 D. W. Chung and P. J. Collier, Infect. Immun., 16, 832 (1977). 18 C. L. Paddon and R. W. Hartley, Gene. 40, 231 (1985). 19 T. Maniatis, E. F. Fritsch, and J. Sambrook, Molecular Cloning, A Laboratory Manual. (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1982). 20 A. Uhlrich, J. Shine, J. Chirgwin, R. Pictet, E. Tischer, W. J. Rutter, and H. M. Goodman, Science, 196, 1313 (1977). 21 C. H. Fiske and Y. Subbarow, J. Biol. Chem., 66, 375 (1925). 22 P. H. Clarke, M. A. Houldsworth, and M. D. Lilly, J. Gen. Microbiol., 51, 225 (1968). 23 A. Body, P. H. Clarke, M. A. Houldsworth and M. D. Lilly, J. Gen. Microbiol., 48, 137 (1967). 24 R. W. Smith and A. C. R. Dean, J. Gen. Microbiol., 72, 32 (1972). 25 Z. Fencl and J. Pazlarova, Folia Microbiol., 27, 340 (1982). 26 J. P. Kotze and A. Kistner, Can. J. Microbiol., 20, 861 (1974). 27 Z. Fenel, J. Ričica, and J. Kodešovä, J. Appl. Chem. Biotechnol., 22, 405 (1972). Volume34, Issue9November 1989Pages 1214-1220 ReferencesRelatedInformation