Abstract
Background Introduction: Current guidelines for the functional evaluation of bioprosthetic heart valves recommend the effective orifice area (EOA) as the product of the transvalvular stroke volume divided by Doppler derived diastolic time velocity integral (TVI). Phase contrast CMR may offer an alternative imaging modality to assess bioprosthetic valve EOA when Doppler methods are technically limited or unreliable. Methods Our circulatory loop includes a mock ventricle and a heart valve imaging chamber that has been fabricated using MRI-compatible components. In this study 3 different sized stented porcine mitral valve bioprostheses were evaluated (27 mm, 29 mm, 31 mm) replicating three different hemodynamic conditions with forward stroke volume of 70 ml, 90 ml and 110 ml respectively at a beat rate of 70 bpm. Imaging was performed with a
Highlights
Introduction: Current guidelines for the functional evaluation of bioprosthetic heart valves recommend the effective orifice area (EOA) as the product of the transvalvular stroke volume divided by Doppler derived diastolic time velocity integral (TVI)
Bioprosthetic mitral valve diastolic flow area was assessed for 3 different sized valves each at 3 flow volume conditions (N = 9)
The lower temporal resolution of phase contrast CMR velocity determination may have led to the lower TVI values and slightly larger EOA calculation compared to Doppler TVI method
Summary
Bioprosthetic mitral valve effective orifice area by phase-contrast CMR. An in vitro comparison with Doppler echocardiography. Dimitrios Maragiannis*, Matthew Jackson, Karen Chin, Kyle Autry, Stephen Igo, Dipan J Shah, Stephen H Little. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
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