Abstract

Biopolymers have gained significant attention as a class of polymer materials with a wide range of applications, especially in the medical and pharmaceutical field. Due to particular characteristics, such as biocompatibility, biodegradability, non-toxicity, and functionality, they have become promising candidates for various surgical applications, including as bioadhesives, sealants, wound dressings, sutures, drug carriers, coating materials, etc. Recent research shows that further modification of biopolymers by advanced techniques can improve their functionality i.e., antibacterial activity, cell viability, drug-releasing capability, good wet adhesion performance, and good mechanical properties. This mini review aims to provide a brief report on the type of biopolymers and recent developments regarding their use in various surgical applications.

Highlights

  • Rapid advances in medical technology have resulted in the improvement of patient care, compliance, and expectations

  • The present mini-review reported biopolymers used in surgical applications, emphasizing the preparative procedures, modification, and consequent properties of biopolymerbased surgical materials

  • The term biomaterial/biopolymer lies on the borderline between two domains: polymer chemistry and medicine, especially surgery

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Summary

Introduction

Rapid advances in medical technology have resulted in the improvement of patient care, compliance, and expectations. In particular, involve an instrumented incision made in an operating room and anesthesia and/or respiratory assistance Surgical materials such as tissue adhesives, sealants, hemostatic agents, wound dressings, absorbent sponges, and suture materials are expected to be non-toxic, biocompatible, and to support cell proliferation for tissue healing. With the recent developments in chemistry and material science, the number of studies evaluating the improvement of functionality, physical–mechanical properties, regenerative and adsorption properties, etc., of biopolymers-based surgical materials is constantly growing For this reason, this mini review aims to highlight the use of natural polymers in surgical applications. Barbu et al [15] reported the contribution of alginates in various compl4eoxf 1w9 ound d ings Alginates and their derivatives have been shown to have anti-bac effects on Gram-positive bacteria (such as Staphylococcaceae or Bacillus cereus) and G negBaatirvbeu betaaclt.e[r1i5a](rseupcohrteads tEhsechcoernitcrhibiautcioolni,oPfsaelugdinoamteosnians vaaerriuoguisncoosam, palnexdwAocuinnedtobacter darnestsiifnugnsg. Their hemostatic effects were produced by platelet activation and thrombin clot formation

Hyaluronic Acid and its Derivatives
Applications of Biopolymers for Surgical Needs
Preparation Method
Adhesives and Sealants
Sutures
Findings
Conclusions and Future Perspectives
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