Year-end Sale % OFF 
Abstract
Axonal pathfinding is an important feature of embryonary development. Based on many biological references, both motor and sensorial function of neurite outgrowth were modelled. The kinetics of filopodia was first described according to their intrinsic motion. The dynamic of the neurite was then simulated with both a visco-elastic elongation, due to the tensions exerted by the growth cone, and a pure outgrowth process, representing the polymerization of the microtubules. Finally, assumptions were made on how filopodia could sense a gradient and be reorganized in an asymmetric distribution. The model reproduces quite well the experimental trajectory of a neurite plunged in a gradient of diffuse molecules.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
