Biophysical Mechanisms of Computation in a Looming Sensitive Neuron

Abstract

The lobula giant movement detector (LGMD) is a large-field visual interneuron believed to be involved in collision avoidance and escape behaviors in orthopteran insects, such as locusts. Responses to approaching—or looming—stimuli are highly stereotypical, producing a peak that signals an angular size threshold. Over the past several decades, investigators have elucidated many of the mechanisms underpinning this response, demonstrating that the LGMD implements a multiplication in log-transformed coordinates. Furthermore, the LGMD possesses several mechanisms that preclude it responding to non-looming stimuli. This chapter explores these biophysical mechanisms, as well as highlighting insights the LGMD provides into general principles of dendritic integration.