Abstract
The aim of this study was to evaluate the bond strength, microleakage, cytotoxicity, cell migration and fluoride ion release over time from a resin-modified glass-ionomer cement (RMGIC) enriched with bioactive glasses (BAGs) and a nanohybrid restorative polymer resin agent used as adhesion material in the cemented brackets. One hundred and twenty bovine lower incisors were divided into three groups: (Transbond Plus Self Etching Primer (TSEP)/Transbond XT (TXT), TSEP/ACTIVA, orthophosphoric acid gel/ACTIVA) and brackets were bonded. A bond strength test and microleakage test were applied. A fluoride release test was applied after 60 days for the TXT and ACTIVA group. To evaluate cytotoxicity and cell migration, a cell viability and scratch migration assay were done for each group. p values < 0.05 were considered significant. Regarding bond strength and microleakage test, no significant differences were found between TSEP/TXT and TSEP/ACTIVA. At 6.4 pH, ACTIVA showed a higher degree of fluoride ion release, which increased with acid pH (3.5), with a maximum fluoride secretion at 30 days. MTT assay revealed that TXT reduces the viability of gingival cells with significant differences (p < 0.001) compared to the untreated cells (control group). ACTIVA provides optimal adhesive and microfiltration properties, releases substantial amounts of fluoride ions in both acid and neutral media, and its biocompatibility is greater than that of traditional composite resin adhesive systems.
Highlights
The appearance of white spots on tooth enamel is one of the undesirable effects of orthodontic treatment, and comprehensive hygiene is essential for its prevention
The aim of this study was to evaluate the bond strength, microleakage, cytotoxicity, cell migration and fluoride ion release over time from an resin-modified glass-ionomer cement (RMGIC) enriched with bioactive glasses (BAGs) and a nanohybrid restorative polymer resin agent used as adhesion material in the cemented brackets
The objective of this study was to determine whether ACTIVATMBioACTIVE-RESTORATIVETM, an RMGIC enriched with BAG, is suitable for cementing brackets and for inhibiting enamel demineralisation
Summary
The appearance of white spots on tooth enamel is one of the undesirable effects of orthodontic treatment, and comprehensive hygiene is essential for its prevention. This requires the patient’s collaboration, which is not always forthcoming [1]. For this reason, it helps if orthodontists use dental materials that release calcium, phosphate and fluoride in order to prevent demineralisation and/or promote remineralisation of the enamel [2]. Saunders et al [9] observed that ACTIVA inhibited the loss of Ca and P ions from the enamel adjacent to brackets
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