Abstract

The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is continuously updated and modified. The addition of new peptides and the introduction of new information about the existing ones (e.g., chemical codes and references to other databases) is in progress. New opportunities include the possibility of annotating peptides containing D-enantiomers of amino acids, batch processing option, converting amino acid sequences into SMILES code, new quantitative parameters characterizing the presence of bioactive fragments in protein sequences, and finding proteinases that release particular peptides.

Highlights

  • The BIOPEP-UWM database is freely-accessible without registration at the following website: http://www.uwm.edu.pl/biochemia/index.php/pl/biopep

  • Bioinformatic databases and software represent basic tools in the research on biologically active peptides, e.g., those derived from food

  • Peptide sequences are annotated in the BIOPEP-UWM database of bioactive peptides using a standard one-letter code describing 20 protein amino acids and their d-enantiomers

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Summary

Introduction

The BIOPEP-UWM database is freely-accessible without registration at the following website: http://www.uwm.edu.pl/biochemia/index.php/pl/biopep. Bioinformatic databases and software represent basic tools in the research on biologically active peptides, e.g., those derived from food. Their role was described in several reviews [1,2,3,4,5,6,7]. Links to the BIOPEP-UWMTM database are recently available via such websites as MetaComBio [11], LabWorm, and OmicX. The aim of the present publication is to provide information helpful in work with the current version of the database and associated tools, including the use of new options introduced in the last three years

Database Organization
Enlarging the Number of Peptides in the Database by BIOPEP-UWMTM Users
Peptide Information
Search Options
Analysis
Useful Links and Other Tabs
1; Supplementary
Literature data mining
Final Remarks
Full Text
Published version (Free)

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