Abstract

The present study has been undertaken to analyze the total accumulated burden of volatile organic compounds (VOCs) in blood of occupationally exposed workers. The headspace technique combined with gas chromatography with flame ionization detector was used for the quantitative analysis of the different volatile organic compounds (isopropyl alcohol, phenol, benzene, dichloromethane, ethanol, ethyl acetate, and toluene) in 80 blood samples from the workers belonging to different occupations i.e., shoe polish workers, thinner handlers, paint workers, furniture polish workers, petrol station attendants, textile dyeing workers, printing press workers, and dry port workers as biomonitoring is one of the most promising methods for analyzing the individual burden of VOCs. Another purpose of this study was to investigate the correlation between detected concentrations of VOCs and associated health issues reported by the workers of these professions. Results of the study revealed the presence of different VOCs in blood samples of approximately 70 workers out of 80, and statistical analysis proved a strong relationship between the reported work experience, working hours, and diseases and the detected concentrations of respective volatile organic compounds.

Highlights

  • IntroductionIsopropyl alcohol, phenol, benzene, dichloromethane, ethanol, ethyl acetate, and toluene, are present in a wide range of commercially available products and have been widely used in different workplaces and industrial sectors (e.g., in manufacturing of paints, adhesives, thinners, glues, plastic, pitch, bitumen, and some pharmaceutical products; in shoe polish industries; in printing presses; and in petroleum industries) and as intermediate in the formation of other chemical substances according to their requirements. ey are direct or indirect source of volatile organic compounds (VOCs) at workplaces.Solvents use in different workplaces has rapidly increased in recent era

  • Isopropyl alcohol, phenol, benzene, dichloromethane, ethanol, ethyl acetate, and toluene, are present in a wide range of commercially available products and have been widely used in different workplaces and industrial sectors and as intermediate in the formation of other chemical substances according to their requirements. ey are direct or indirect source of volatile organic compounds (VOCs) at workplaces

  • VOCs are considered as environmental contaminants because they persist in the air [1]

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Summary

Introduction

Isopropyl alcohol, phenol, benzene, dichloromethane, ethanol, ethyl acetate, and toluene, are present in a wide range of commercially available products and have been widely used in different workplaces and industrial sectors (e.g., in manufacturing of paints, adhesives, thinners, glues, plastic, pitch, bitumen, and some pharmaceutical products; in shoe polish industries; in printing presses; and in petroleum industries) and as intermediate in the formation of other chemical substances according to their requirements. ey are direct or indirect source of volatile organic compounds (VOCs) at workplaces.Solvents use in different workplaces has rapidly increased in recent era. Ey are direct or indirect source of volatile organic compounds (VOCs) at workplaces. Individuals living or working in such conditions are commonly exposed to pollutants released from solvents. Most of these organic solvents are considered as environmental contaminants because of their high volatility and hazardous nature, even when they are present in low concentrations. In recent years VOCs in the atmosphere has gained much attention due to their direct and indirect effects. E direct effects of these toxic compounds are their potential to cause serious health effects [2]. Indirect effects of VOCs are related to their typical reactions in troposphere. Health effects due to occupational exposure of VOCs include kidney and liver damage and effects on central nervous system

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