Abstract
A simple and rapid method for the determination of benzene and toluene in whole blood by headspace-solid-phase microextraction (HS-SPME) is described. Using SPME fibres coated with 65 μm carboxene/polydimethylsiloxane, limits of quantification (LOQ) of 5 ng/L for benzene and 25 ng/L for toluene are achieved. As a result of its large linear range (i.e. 5–5000 ng/L for benzene) the method is suitable for biomonitoring of both occupationally and environmentally exposed people. The reproducibility of the determination of benzene is ≤ 8%. An interlaboratory comparison demonstrated that the method proposed here compares favorably with existing methods (dynamic headspace, purge and trap).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
