Abstract

We report in this paper a novel strategy for "bottom-up" assembly of two types of metallic and semiconductor nanoparticles. By only using a small biomolecule, coenzyme A, as a "linker" to direct the assembly of metallic gold and semiconductor titanium dioxide nanoparticles, the usual biomolecule-directed system can be greatly simplified. Effects of experimental conditions on the formation of binary nanoparticles are studied. This strategy using single small biomolecule to direct assembly of nanoparticles is proven to be efficient, facile and non-toxic and should be extendable to other building blocks.

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