Abstract
Biomolecular networks and human diseases.
Highlights
Most existing computational methods were applied on static protein-protein interaction (PPI) networks to identify the protein complex
Most existing computational methods were applied on static PPI networks to identify the protein complex
In their paper “Identifying dynamic protein complexes based on gene expression profiles and PPI networks,” M
Summary
Most existing computational methods were applied on static PPI networks to identify the protein complex. We reported the recent progress in computational approaches that have been developed for analyzing complex networks constructed from high-throughput data and their applications to human diseases. Lei et al proposed a novel clustering model which combined the optimization mechanism of artificial bee colony (ABC) with the fuzzy membership matrix to detect protein complexes from PPI networks.
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