Abstract
There are two basic issues inherent in contemporary molecular and biomolecular computing and urgent for its future development. They are: (i) fundamentals, that is general principles, starting points and correlation's between different approaches to design biomolecular information processing devices, (ii) working criteria, that is goals and principles for the choice of the device designing characteristics to achieve these goals. These issues are common to all major approaches of contemporary biomolecular computing. Increasing behavioral complexity of an information processing device seems to be a criterion for designing biomolecular means capable of solving problems of high computational complexity.
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