Abstract

Sweet taste detection is of great significance in fields of disease prevention, food safety inspection, and drug regulation. In this study, a novel biomimetic sensor was constructed for sweet taste detection by compositing graphene oxide, hemin, and 3-aminophenylboronic acid (APBA). First, optimal fabrication of the sensor was investigated by comparing different composition proportions of graphene oxide and APBA functionalized hemin in saccharide measurements. Then, typical substances of natural sugars (i.e., glucose and fructose) and artificial sweeteners (i.e., saccharin and aspartame) were measured with the sensor through optical absorption spectroscopy. The spectra displayed apparent but different absorbance changes in the presence of those two kinds of saccharides, showing different sensing mechanisms of the biomimetic sensor for sugars and sweeteners like sweet receptors. Finally, dose-dependent and specific responses of the sensor were observed by comparing with other taste substances. The results suggested that the sensor can detect and distinguish natural sugars and artificial sweeteners in a biomimetic way. The research provided a low-cost, long-lifetime, and efficient approach for sweet taste detection, indicating its promising applications in fields such as food and beverage analysis.

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