Abstract
N1- and N2-derivatives of 3-nitro-l,2,4-triazole (3-NTR) were subjected to the non-biological evaluation methods involving biomimetic, chemical, and spectroscopic procedures for the radio-sensitizing potential. Consequently, the N1-derivatives of 3-NTR were suggested to be more promising radiosensitizers to hypoxic cells in vivo than the N2-derivatives.
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