Abstract

Biometric measurement of the anterior segment is of great importance for the ophthalmology, human eye modeling, contact lens fitting, intraocular lens design, etc. This paper serves as a comprehensive review on the historical development and basic principles of the technologies for measuring the geometric profiles of the anterior segment. Both the advantages and drawbacks of the current technologies are illustrated. For in vivo measurement of the anterior segment, there are two main challenges that need to be addressed to achieve high speed, fine resolution, and large range imaging. One is the motion artefacts caused by the inevitable and random human eye movement. The other is the serious multiple scattering effects in intraocular turbid media. The future research perspectives are also outlined in this paper.

Highlights

  • Biometricmeasurement measurement ofanterior the anterior of great for importance for the Abstract: of the segmentsegment is of greatis importance the ophthalmology, ophthalmology, humancontact eye modeling, contact lens fitting, intraocular lensThis design, etc.serves

  • Several commercial instruments are multifunction systems that combine the Placido disk corneal topography with the tomography technologies to increase the accuracy of the anterior corneal curvature measurement [26,37,38], which are described

  • A great variety of technologies can be employed to perform the analysis of the anterior segment, evolving from qualitative analysis to quantitative measurement, and from topography to tomography

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Summary

Approaches in Measuring the Anterior Segment

There are various available technologies for measuring the anterior segment at present, including pattern projection, interferometry, Scanning-slit, Scheimpflug imaging, very high frequency digital ultrasound or ultrasound biomicroscopy (UBM) and optical coherence tomography (OCT) [21]. Several commercial instruments are multifunction systems that combine the Placido disk corneal topography with the tomography technologies to increase the accuracy of the anterior corneal curvature measurement [26,37,38], which are described

Placido
Placido discdisc and representative patterns of corneal shapes
Rasterstereography
Triangulation principle cornealsurface surface measurement
Holographic Technique
Moiré Technique
Schematic
Setup forfor measuring the corneal surfacebased based
Fourier Transform Profilometry
Scanning-Slit
Scheimpflug Imaging
Ultrasound Biomicroscopy
10 MHz ultrasound frequency for the whole imaging with an approximately
Optical Coherence Tomography
Time Domain OCT
15. Schematic
Fourier
16. Schematic diagram a spectraldomain domain OCT
Challenges and Perspectives
Motion Artefacts
Intraocular Multiple Scattering Effects
Findings
Conclusions
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