Abstract
Determinations of the diurnal and nocturnal 17-Ketosteroids excretion in the urine of two male adults were made every day for 2-3 years.Seasonal variations in 17-KS excretion were different from the data which had been so far reported by some authors in Japan, i. e., in the two subjects, the peaks were in May to July and in March respectively, not in the winter months. This may be partly explained by the difference in regional climates and by variations of heating and cooling device.Effects of individual meteorological factors, such as temperature, humidity, air pressure and precipitation, on the urinary 17-KS excretion were slight when seasonal variations were excluded. The integrated effect of these factors, the weather, played a major role in the 17-KS variation.The level of the 17-KS was lower on fine days and higher on rainy days with medium values being obtained on cloudy days.Relationship between weather changes and 17-KS excretion is obvious: a decrease of the latter is associated with improvement of the weather and an increase with worsening of it.It is assumed that the dynamic change in the integrated effect of meteorological factors is more important as a stimulating agent of the pituitary-adrenal system than any individual factor or the effect of a static weather system.
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More From: Nihon eiseigaku zasshi. Japanese journal of hygiene
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