Abstract

The economic-plant-mulberry is infected by different pathogens causing diseases and significantly reduces silk production. Though pesticides are the most effective means of control, but they are expensive and not environment friendly. On the other hand, the ongoing spread of the novel coronavirus, forming epidemic, affecting human civilizations, because recently, no appropriate antiviral drugs for effective treatments or vaccines against COVID-19. To meet the challenge, it is reported that the therapeutic value of traditional-, complementary- and alternative-biomedicines-Artemisia nilagirica, has been used for centuries, to overcome various medical disorders. So, to concur with the situation, it will require new and more efficient solutions, technologies, and products. Present pretreatment with ultra-high-diluted biomedicines-Cina, prepared from the flowering meristems of Artemisia nilagirica (Clarke) pamp, mixed with water at an extremely low dose, were applied by foliar spray once daily for 15 days @ 10 ml/plant, against naturally occurring, root-knot-, leaf spot-, powdery mildew-, mosaic- and tukra- mulberry diseases, in field trials and silkworms rearing. Pretreatment-investigations have revealed that ultra-high-diluted-Cina, highly effective in ameliorating different mulberry-diseases by inducing their natural defense-response against pathogens-infection and leaving no residual-toxicity in the leaves to affect the growth of silkworms also. It can be concluded that the ultra-high-diluted, eco-friendly easily-available, easily applicable-Cina, at an extremely low dose, not only used as a potential-biomedical-drug against various plant-diseases, by inducing natural-defense- response, but also, it may be effective against COVID-19 for vaccinations and clinical trials by boosting the natural immune system for the improvement of Science and Technology communication cost-effectiveness green-economy and biodiversity conservations as well as bio-applications issues. And the future clinical-scientists develop all aspects of clinical-case-reports by publishing in the appropriate medical research archives, with the sincere hope that this crisis will soon be over and the whole world, may fight against the COVID-19 war, retaining normal forms of human civilizations globally.

Highlights

  • Novel coronavirus disease- COVID-2019 epidemic problems, identified by the Chinese authorities [37], forming pandemic with profound effects on our private and professional life, the world economy, and the social life and humanity [38] with unusual viral pneumonia [39] and scientists are working with the genome of COVID [40], [41] which could potentially emerge in humans in the future [41]

  • Air-dried and powdered flowering meristems of A. nilagirica, (Plate 1), were extracted with 90% ethanol and the crude residues were dissolved in 90% ethanol at 1mg/ml concentration and were formed homeopathic mother tincture of A. nilagirica called Cina MOTHER TINCTURE (MT) (Original Solution or Crude Extract i.e. Mother Tincture) [5], [7], [11], [16], [18], [22], [25], [33], [60]

  • The crude extract of A. nilagirica, named Cina MT were diluted with 90% ethanol (1:100) proportionate in a round vial which was filled up to two-thirds of its space, tightly corked and were given 10 powerful downward strokes of the arm, forming the 1st centesimal potency named Cina1C and all the subsequent potencies were prepared in this way; -Cina 30C and -Cina 200C medicine were prepared respectively [5], [7], [11], [16], [18], [22], [25], [33], [60]

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Summary

Introduction

The mulberry, is a major foreign exchange earner of India, which is short about 30% to fulfill the home requirements [1], due to the mulberry diseases, caused by pathogens, which affects the silk -yield in terms of quality and quantity [1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22],[23], [24], [25], [26], [27]. Synthetic and chemical pesticides are the most effective means of control, but they are Biomedicines-Cina Against Covid-19: Controlled Plant Diseases Enriched Science and Technology Communication Green Economy both expensive and environmentally unfriendly, toxic to man and not-biodegradable [28], [29]. Novel coronavirus disease- COVID-2019 epidemic problems, identified by the Chinese authorities [37], forming pandemic with profound effects on our private and professional life, the world economy, and the social life and humanity [38] with unusual viral pneumonia [39] and scientists are working with the genome of COVID [40], [41] which could potentially emerge in humans in the future [41]. How can doctors minimize the danger? [49]

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