Abstract
The recent introduction of high-resolution molecular imaging technology is considered by many experts as a major breakthrough that will potentially lead to a revolutionary paradigm shift in health care and revolutionize clinical practice. This paper explores the challenges and strengths of the current major imaging modalities, as well as the biophysics engineering their repertoire of capabilities. Advancements in the mechanical aspects of both PET and SPECT imaging will advance molecular imaging diagnostic capabilities and have a direct impact on clinical medicine and biomedical research practice. A better understanding of the strengths and limitations of functional imaging modalities in the context of their particular hardware and software mechanics will shed light onto how we can advance their diagnostic capabilities on a biological level. Herein, this paper demonstrates the fundamental biomechanical differences between PET and SPECT imaging, and how these fundamental differences translate into clinically relevant data acquisition for brain disorders.
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