Biomedical Effects of Acupuncture

Abstract

Biomedical effects of acupuncture Introduction: The use of acupuncture as a method of pain relief in western medicine is based on a wide range of clinical trials, and there is no doubt that it has significant effect in the treatment of acute and chronic pain. Method: We were going a summary on past decades performed acupuncture studies on effects. Studies found that in chronic pain the concentration of endorphins in the spinal fluid is markedly reduced. Cholecystokinin octapeptide has been shown to function in the CNS as a neuropeptide with potent antiopioid activity. Electro acupuncture stimulation caused a substantial increase of immunoreactivity in CSF perforates of the rat spinal cord. The diffuse noxious inhibitory controls may be involved in the mechanisms. DNIC are part of the biological pain control system. Our summary examines the analgesic effect of the TRR 469 adenosine receptor agonist. Upon acupuncture points stimulation Zu San Li (St 36) significantly higher concentrations of adenosine were recorded. Results: Acupuncture induces a variety of biological responses, which occur both locally as well as in a remote location. Studies on the stress response show that acupuncture techniques can reduce the neither concentration of nor adrenaline at cerebral perfusion and in the blood circulation, reduce the production of epinephrine in animals exposed to restraint stress, induce long-term behavioural and cardiovascular depression in behaviour and anxiolytic effects common in animals in captivity. Forced restraint has shown to be a simple physiological stressor that causes significant increase of heart activity, blood pressure and levels of nor epinephrine and epinephrine, activation of the simpatico-adrenal system and the hypothalamic-pituitary axis. Discussion: CCK 8 is in fact increasingly released at frequencies from 100 Hz to 15 Hz. Opioid peptides are activated and CCK 8 is not produced at low frequencies 1-2 Hz. The known effect of the endogenous opioids which are produced in electro acupuncture stimulation and hindered by naloxone does not apply unequivocally, since the low frequency EA stimulation have been found to activate opioid peptides derived from propio-enkephalins, while the high frequency of 100 Hz activates the preprodynorphin group, in laboratory animals as well as in humans. The needle stimulation or low frequency electro acupuncture was effective in certain nociceptive some states, whereas the high frequency stimulation proves more effective in comparison with manual acupuncture. The lack of acupuncture effectiveness may be attributed to the high levels of cholecystokinin opioid antagonist in the brain (1). Conclusion: Acupuncture and associated therapies have come to the fore. More further basic and applied researches need for deeper understand its effect. They are always related to the patients lifestyle for elevate QoL.