Abstract
Functionally graded porous (FGP) interbody cage might offer a trade-off between porosity-based reduction of stiffness and mechanical properties. Using finite element models of intact and implanted lumbar functional spinal unit (FSU), the study investigated the quantitative deviations in load transfer and adaptive changes in bone density distributions around FGP interbody cages. The cage had three graded porosities: FGP-A, -B, and –C corresponded to a maximum porosity levels of 48%, 65% and 78%, respectively. Efficacy of the FGP cages were evaluated by comparing the numerically predicted results of solid-Ti and uniformly porous 78% porosity (P78) cage. Variations in stiffness and interface condition affected the strain distribution and bone remodelling around the cages. Peak strains of 0.5–1% were observed in less number of peri-prosthetic bone elements for the FGP cages as compared to the solid-Ti cage. Strains and bone apposition were considerably higher for the bonded implant-bone interface condition than the debonded case. For the FGP-C with bonded interface condition, bone apposition of 11–20% was predicted in the L4 and L5 regions of interest (ROIs); whereas the debonded model exhibited 6–10% increase in bone density. The deviations in bone density change between FGP-C and P78 model were 3–8% for L4 and L5 ROIs. FGP resulted in a reduced average micromotion (∼70–106 μm) as compared to solid-Ti (116 μm), for all physiologic movements. Compared to solid-Ti and uniformly porous cages, the FGP cage seems to be a viable alternative considering the conflicting nature of strength and porosity.
Published Version
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