Abstract

Biomaterials and biotechnology are increasing becoming an important area in modern medicine. The main aim in this area is the development of materials, which are biocompatible to normal tissue. Tissue-implant interactions with molecular, biological and cellular characteristics at the implant-tissue interface are important for the use and development of implants. Implantation may cause an inflammatory and immune response in tissue, foreign body reaction, systemic toxicity and imminent infection. Tissue-implant interactions determine the implant life-period. The aims of the study are to consider the biological response to implants. Biomaterials and host reactions to implants and their mechanisms are also briefly discussed.

Highlights

  • The medical field of biomaterials and bioengineering is nowadays becoming increasingly important

  • Materials, which are essentially well known in the technological field, had initially not been developed as biomaterials

  • The aim of the study of biomaterials is to understand the biological response of tissue and organism to artificial implants

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Summary

Introduction

The medical field of biomaterials and bioengineering is nowadays becoming increasingly important. The aim of the study of biomaterials is to understand the biological response of tissue and organism to artificial implants. A surgical implantation of a biomaterial into the body triggers an organism-inflammatory reaction with the associated healing of the damaged tissue.

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