Abstract
Biomarkers in psychiatry: how close are we?
Highlights
Until recently, there has been an ongoing worldwide quest in search for disease-specific molecular biomarkers in medicine
Biological psychiatry is focusing on the use of all available advanced molecular techniques that can allow for biomarker detection assisted by the afore-employed imaging and analysis techniques
These methodologies rely on sophisticated computational-multi disciplinary field of systems biology utilizing advanced bioinformatics processing tools that can interpret the high throughput molecular omics data relevant to neuropsychiatric research
Summary
There has been an ongoing worldwide quest in search for disease-specific molecular biomarkers in medicine. Biomarker research has achieved great success in various clinical fields such as cardiovascular disease, hepatic disorders, neurotrauma leading to key markers including the discovery of troponin as marker for myocardial infarction, and 14-3-3 protein for Creuzfolt-Jacob Disease, S100β/UCH-L1/αII-spectrin for brain trauma (Hayes et al, 2011; Kobeissy et al, 2011; Mondello et al, 2011).
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