Abstract

Biomarkers for Psychiatric Disorders: Where Are We Standing?

Highlights

  • The most needed type of biomarkers to be applicable in a short-term future are those which could predict or indicate the likelihood of a successful treatment

  • There are no biomarkers of any kind available to any of the psychiatric disorders, and perhaps establishing those will be one of the most difficult tasks that medical scientists will ever face, This is due to several reasons: (1) the multifactorial characteristic of psychiatric disorders, (2) these are multigenic disorders in which each gene has a small effect; (3) the environment exerts a heavy influence in the establishment of the disease

  • Each psychiatric condition is a heterogeneous entity: for example, bipolar disorder is one disease composed by very opposite phases and symptoms, if we consider maniac and depressive episodes

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Summary

Introduction

The most needed type of biomarkers to be applicable in a short-term future are those which could predict or indicate the likelihood of a successful treatment. Each psychiatric condition is a heterogeneous entity: for example, bipolar disorder is one disease composed by very opposite phases and symptoms, if we consider maniac and depressive episodes. It has been shown that up to 31% of the bipolar disorder patients may be initially diagnosed with schizophrenia [1].

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