Abstract
Determining the total amount of HIV DNA in people undergoing antiretroviral therapy could accelerate the development of novel therapies and potential cures for HIV infection.
Highlights
Determining the total amount of HIV DNA in people undergoing antiretroviral therapy could accelerate the development of novel therapies and potential cures for HIV infection
Most people on long-term ART have about 10–1000 copies of HIV DNA per million white blood cells that can be infected by the virus (Eriksson et al, 2013)
In eLife, John Frater at the John Radcliffe Hospital in Oxford and co-workers in the SPARTAC collaboration report an important advance in the search for a biomarker for the latent reservoir
Summary
Determining the total amount of HIV DNA in people undergoing antiretroviral therapy could accelerate the development of novel therapies and potential cures for HIV infection. These cells can persist in the body for life, and they allow the virus to re-emerge and ignite new rounds of infection if antiretroviral therapy (or ART) is ever interrupted.
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