Abstract
Good medicine is based on good science, inquiry driven and open to new paradigms. For a complex disease such as cancer, a complex treatment regime that is well structured and multifactorial is indispensable. In the present day, Complementary and Alternative Medicine (CAM) therapies are being used frequently for cancer, alongside modern biological therapies and allopathic medicine, in what is called integrative oncology. In all conscience, the use of natural, less invasive interventions whenever possible is ideal. However, a comprehensive understanding of not only the etiopathology of individual cancers, but also the detailed genetic and epigenetic characteristics, the cancer hallmarks, that clearly show the blueprint of the cancer phenotype is a requisite. Different tumors have a common behavioral pattern, but their specific features at the genetic and epigenetic levels vary to a great extent. Henceforth, with so many failed attempts to therapy, drug formulations and combinations need a focused pre-assessment of the inherent features of individual cancers to destroy the tumors holistically by targeting these features. This review therefore presents innocuous therapeutic regimes by means of CAM and integrative medicine approaches that can specifically target the hallmarks of cancer, using the case of cervical cancer.
Highlights
Introduction and Cristina Adela IugaFor eons, treating cancer using conventional chemo and radiation therapy has been in practice regardless of the many side effects that these two therapies cause
The idea is based on the biological response to low exposures with no effect at high doses. This means that the oncolytic virus (OV) concept of using overexpressed tumor-associated carbohydrate antigens (TACAs), proteins injected in thethat body notinexceed hormetic zone is and requires and enzymes areshould antigenic cancer the cellsdose
Conization is the removal of a cone-shaped piece of tissue from the cervix and cervical canal and is the most widely used treatment for CINs, carcinoma in situ and stage I tumors in most countries
Summary
Treating cancer using conventional chemo and radiation therapy has been in practice regardless of the many side effects that these two therapies cause. In addition to CAM and as a part of alternatives to conventional chemo and radiation therapy, modern cancer research has focused on the use of biological therapies to remove tumors with the least risk of side effects. A full account of the present understanding of HPV and CaCx is given in order to examine the inherent features that play important roles in CaCx and its subsequent response to therapy, which should be the target when designing biological therapies and when considering the use of CAM therapies by means of an integrative medicine approach. For the relevance of this discussion, a brief introduction to the morphology of cancer is given, followed by a detailed etiopathology of CaCx, to set foot on inherent features to be discussed and the analysis of those inherent features which CAM and integrative medicine can target to achieve the desired therapeutic outcome proceed
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