BIOLOGICAL SAFETY OF PUBLIC EVENTS: FEATURES OF LABORATORY DIAGNOSTICS

Abstract

To scientifically prove the nomenclature of the priority pathogenic biological agents (PBA) and the infectious diseases caused by them for laboratory diagnostics when ensuring biological safety of public events. PBA assessment (viruses, bacteria, biological toxins I - IV of groups of pathogenicity) was carried out, using the criteria allowing to predict their potential negative impact at the qualitative level. The evidence-based nomenclature of PBA posing the greatest threat of biological safety regardless oftheir confmedness to the territory of risk and time of risk is developed. The list included the bacterial (plague, anthrax, cholera) and viral agents (orthopoxviruses, filoviruses, arenaviruses, coronaviruses, orthomyxoviruses) of the I - II groups of the pathogenicity. The nomenclature of the widespread natural and focal (tularemia, leptospirosis, the Q fever, hemorrhagic fever with a renal syndrome, ornithosis) and the ubiquitous (brucellosis, hemorrhagic colibacillosis, a hemolytic-uremic syndrome, intestinal yersiniosis, pseudotuberculosis, Legionnaires' disease) infections capable to cause the serious complication of the sanitary and epidemiologic situation is prepared. On the basis of the carried-out assessment of dangerous biological factors the universal list of PBA for priority ensuring readiness for laboratory diagnostics during public events was created.