Abstract

Purpose: Progressive degeneration of articular cartilage, resulting from a local cartilage defect, is a key feature of osteoarthritis (OA), the most common form of joint disease in the western world today. Middle-aged people who participate in sporting activities have expectations for recovery and therefore are unsuitable for joint replacement surgery, as high activity demands may lead to early failure. Therefore, the goal of this study was to adjust the conventional operation technique and to compare three different methods for biological repair in a large animal model with long-term follow-up.

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