Abstract
Abstract 5-(o-Carboran-1-yl)-2′-deoxyuridine containing dodecathymidylic acids (2-7) manifested increased lipophilicity, resistance to digestion by calf spleen phosphodiesterase, and snake venom phosphodiesterase. They were substrates for T4 polynucleotide kinase, primers for E. coli polymerase I, human α DNA polymerase, and HIV-1 reverse transcriptase. They also form heteroduplexes that are substrates for E. coli RNase H.
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